業績

Achievement

2025年度
論文
  • Advances in Conventional and Extended Fluorescence Correlation Spectroscopy for the Analysis of Biological Clusters and Aggregates
  • Kitamura A
  • Spectrosc. J., 3(4), 31 (2025).
  • DOI: 10.3390/spectroscj3040031
  • The DNA replication machinery transmits dual signals to prevent unscheduled licensing and execution of centrosome duplication
  • Matsuhashi K, Ito KK, Nagai K, Sanada A, Watanabe K, Takumi K, Toyoda A, Fukuyama M, Yamamoto S, Chinen T, Stewart GS, Hata S, Kitagawa D
  • Nat. Commun., 16(1), 7799 (2025)
  • DOI: 10.1038/s41467-025-63002-3
  • Cell-free production of target-directed liposomes utilizing membrane localization peptides
  • Kuno K, Shimane Y, Sakai Y, Kuruma Y
  • J. Control. Release, 388(1), 114343 (2025)
  • DOI: 10.1016/j.jconrel.2025.114343
  • Lipid Modification and Membrane Localization of Proteins in Cell-Free System
  • Matsumoto R, Niwa T, Kuno K, Shimane Y, Kuruma Y, Kanamori T
  • ACS Synth. Biol., 14(7), 2729-2738 (2025)
  • DOI: 10.1021/acssynbio.5c00155
  • Comparative analysis of multiple DNA double-strand break repair pathways in CRISPR-mediated endogenous tagging.
  • Tei C, Hata S, Mabuchi A, Okuda S, Ito KK, Genova M, Fukuyama M, Yamamoto S, Chinen T, Toyoda A, Kitagawa D
  • Commun. Biol., 8(1), 749 (2025)
  • DOI: 10.1038/s42003-025-08187-5
  • Cryo-ET of actin cytoskeleton and membrane structure in lamellipodia formation using optogenetics
  • Inaba H, Imasaki T, Aoyama K, Yoshihara S, Takazaki H, Kato T, Goto H, Mitsuoka K, Nitta R, Nakata T
  • iScience, 28(6), 112529 (2025).
  • DOI: 10.1016/j.isci.2025.112529
  • Sister chromatid cohesion through the lens of biochemical experiments
  • Murayama Y
  • Curr. Opin. Cell Biol., 93, 102464 (2025).
  • DOI: 10.1016/j.ceb.2025.102464

2024年度
論文
  • Impact of Polydispersity on Phase Separation: Insights from Polyethylene Glycol and Dextran Mixtures.
  • Kamo A, Nikoubashman A, Yanagisawa M
  • J. Phys. Chem. B, 129(12), 3263-3271 (2025).
  • DOI: 10.1021/acs.jpcb.4c08640
  • Malabaricone C isolated from edible plants as a potential inhibitor of SARS-CoV-2 infection.
  • Mutmainah, Murai Y, Fujimoto A, Kawamura R, Kitamura A, Koolath S, Usuki U, Sasaki M, Orba Y, Igarashi Y, Sawa H, Sato A, Monde K
  • Sci. Rep., 15(1), 8518 (2025).
  • DOI: 10.1038/s41598-024-83633-8
  • Meiosis: When centromeres choose compromise over conflict.
  • Shreyas S, Fukagawa T
  • Curr. Biol., 35(5), R196-R198 (2025).
  • DOI: 10.1016/j.cub.2025.01.059
  • Organization of the chromosomal passenger complex clusters at inner centromeres in mitosis.
  • Matsui S, Nozawa RS, Hirota T.
  • Curr. Biol., 92, 102462 (2025).
  • DOI: 10.1016/j.ceb.2024.102462
  • Multimodal mechanisms of human centriole engagement and disengagement.
  • Ito KK, Kasuga T, Matsuhashi K, Sakamoto H, Nagai K, Fukuyama M, Yamamoto S, Chinen T, Hata S, Kitagawa D
  • EMBO J., 44, 1294-1321 (2025).
  • DOI: 10.1038/s44318-024-00350-8
  • Dysregulation of PI4P in the trans Golgi regions activates the mammalian Golgi stress response.
  • Sasaki K, Toide M, Adachi T, Morishita F, Watanabe Y, Sakurai HT, Wakabayashi S, Kusumi S, Yamaji T, Sakurai K, Koga D, Hanada K, Yohda M, Yoshida H
  • J. Biol. Chem., 301(1), 108075 (2025).
  • DOI: 10.1016/j.jbc.2024.108075
  • Interaction mapping between nucleoporins in the fission yeast Schizosaccharomyces pombe using mass-spectrometry.
  • Asakawa H, Nagao K, Fukagawa T, Obuse C, Hiraoka Y, Haraguchi T
  • J. Biochem., 177(4), 273-286 (2025).
  • DOI: 10.1093/jb/mvae095
  • Molecular details and phosphoregulation of the CENP-T-Mis12 complex interaction during mitosis in DT40 cells.
  • Takenoshita Y, Hara M, Nakagawa R, Ariyoshi M, Fukagawa T
  • iScience, 27(12), 111295 (2024).
  • DOI: 10.1016/j.isci.2024.111295
  • Near-identical macromolecules spontaneously partition into concentric circles.
  • Gong H, Sakaguchi Y, Suzuki T, Yanagisawa M, Aida T
  • Nature, 636(8041), 92-99 (2024).
  • DOI: 10.1038/s41586-024-08203-4
  • Spatiotemporal Evolution of Heterogeneous Structures in Agarose Gels Revealed by Particle Tracking.
  • Yanagisawa N, Hara T, Yanagisawa M
  • Soft Matter., 21(2), 262-268 (2024).
  • DOI: 10.1039/D4SM01122H
  • Isolation of Mitotic Centrosomes from Cultured Human Cells.
  • Miyazawa M, Yamamoto S, Goyama S, Kitagawa D
  • The Mitotic Spindle. Methods Mol. Biol., 2872, 233-244 (2024).
  • DOI: 10.1007/978-1-0716-4224-5_16
  • A Method for Analyzing Acentrosomal Mitotic Spindles in Human Cells.
  • Okuda S, Chinen T, Kitagawa D
  • The Mitotic Spindle. Methods Mol. Biol., 2872, 221-231 (2024)
  • DOI: 10.1007/978-1-0716-4224-5_15
  • Pattern recognition of drying lysozyme-glucose droplets using machine learning classifiers.
  • Pal A, Yanagisawa M
  • Physica A Stat. Mech. Appl., 654, 130141 (2024).
  • DOI: 10.1016/j.physa.2024.130141
  • Chromosomal rearrangements associated with SMC5/6 deficiency in DNA replication.
  • Kusano Y, Kinugasa Y, Tashiro S, Hirota T.
  • Genes Cells, 29(12), 1251-1263 (2024).
  • DOI: 10.1111/gtc.13180
  • Molecular mechanism of parental H3/H4 recycling at a replication fork.
  • Nagae F, Murayama Y, Terakawa T
  • Nat. Commun., 15(1), 9485 (2024).
  • DOI: 10.1038/s41467-024-53187-4
  • CENP-C-Mis12 complex establishes a regulatory loop through Aurora B for chromosome segregation.
  • Kong W, Hara M, Tokunaga Y, Okumura K, Hirano Y, Miao J, Takenoshita Y, Hashimoto M, Sasaki H, Fujimori T, Wakabayashi Y, Fukagawa T
  • Life Sci. Alliance, 8(1), e202402927 (2024).
  • DOI: 10.26508/lsa.202402927
  • Autophagy adaptors mediate Parkin-dependent mitophagy by forming sheet-like liquid condensates.
  • Yang Z, Yoshii SR, Sakai Y, Zhang J, Chino H, Knorr RL, Mizushima N
  • EMBO J., 43(22), 5613-5634 (2024).
  • DOI: 10.1038/s44318-024-00272-5
  • Secretion of endoplasmic reticulum protein VAPB/ALS8 requires topological inversion.
  • Kamemura K, Kozono R, Tando M, Okumura M, Koga D, Kusumi S, Tamai K, Okumura A, Sekine S, Kamiyama D, Chihara T
  • Nat. Commun., 15(1), 8777 (2024)
  • DOI: 10.1038/s41467-024-53097-5
  • Role of motility and nutrient availability in drying patterns of algal droplets.
  • Pal A, Sengupta A, Yanagisawa M
  • Sci. Rep., 14(1), 23481 (2024).
  • DOI: 10.1038/s41598-024-73836-4
  • The potential of artificial cells functioning under in situ deep-sea conditions.
  • Kuruma Y, Nomaki H, Isobe N, Matsuoka D, Shimane Y.
  • ACS Synth. Biol., 13(10), 3144-3149 (2024).
  • DOI: 10.1021/acssynbio.4c00441
  • Short Repeat Ribonucleic Acid Reduces Cytotoxicity by Preventing the Aggregation of TDP-43 and Its 25 KDa Carboxy-Terminal Fragment.
  • Fujimoto A, Kinjo M, Kitamura A
  • JACS Au, 4(10), 3896-3909 (2024).
  • DOI: 10.1021/jacsau.4c00566
  • Single-nucleosome imaging unveils that condensins and nucleosome-nucleosome interactions differentially constrain chromatin to organize mitotic chromosomes.
  • Hibino K, Sakai Y, Tamura S, Takagi M, Minami K, Natsume T, Shimazoe MA, Kanemaki MT, Imamoto N, Maeshima K
  • Nat. Commun., 15(1), 7152 (2024).
  • DOI: 10.1038/s41467-024-51454-y
  • Interaction of receptor-binding domain of the SARS-CoV-2 Omicron variant with hACE2 and actin.
  • Fujimoto A, Kawai H, Kawamura R, Kitamura A
  • Cells, 13(16), 1318 (2024).
  • DOI: 10.3390/cells13161318
  • Marangoni droplets of dextran in PEG solution and its motile change due to coil-globule transition of coexisting DNA.
  • Furuki T, Sakuta H, Yanagisawa N, Tabuchi S, Kamo A, Shimamoto DS, Yanagisawa M
  • ACS Appl. Mater. Interfaces, 16(32), 43016-43025 (2024).
  • DOI: 10.1021/acsami.4c09362
  • Disordered region of nuclear membrane protein Bqt4 recruits phosphatidic acid to the nuclear envelope to maintain its structural integrity.
  • Hirano Y, Sato T, Miura A, Kubota Y, Shindo T, Fukase K, Fukagawa T, Kabayama K, Haraguchi T, Hiraoka Y
  • J. Biol. Chem., 300(7), 107430 (2024).
  • DOI: 10.1016/j.jbc.2024.107430
  • Hetero-oligomerization of TDP-43 carboxy-terminal fragments with cellular proteins contributes to proteotoxicity.
  • Kitamura A, Fujimoto A, Kawashima R, Lyu Y, Sasaki K, Hamada Y, Moriya K, Kurata A, Takahashi K, Brielmann R, Bott LC, Morimoto RI, Kinjo M
  • Commun. Biol., 7(1), 743 (2024).
  • DOI: 10.1038/s42003-024-06410-3
  • Tubulin glycylation controls ciliary motility through modulation of outer-arm dyneins.
  • Kubo T, Sasaki R, Oda T
  • Mol. Biol. Cell, 35(12), 1200-1211 (2024).
  • DOI: 10.1091/mbc.E24-04-0154
  • Vertebrate centromeres in mitosis are functionally bipartite structures stabilized by cohesion.
  • Sacristan C, Samejima K, Ruiz LA, Deb M, Lambers MLA, Buckle A, Brackley CA, Robertson D, Hori T, Webb S, Kiewisz R, Bepler T, van Kwawegen E, Risteski P, Vukusic K, Tolic IM, Muller-Reichert T, Fukagawa T, Gilbert N, Marenduzzo D, Earnshaw WC, Kops GJPL
  • Cell, 187(12), 3006-3023.e26 (2024).
  • DOI: 10.1016/j.cell.2024.04.014
  • Three-dimensional analysis of the intracellular architecture by scanning electron microscopy.
  • Koga D, Kusumi S, Yagi H, Kato K
  • Microscopy, 73(3), 215-225 (2024).
  • DOI: 10.1093/jmicro/dfad050
  • Bipartite binding interface recruiting HP1 to chromosomal passenger complex at inner centromeres.
  • Sako K, Furukawa A, Nozawa RS, Kurita JI, Nishimura Y, Hirota T.
  • J. Cell Biol., 223(9), e202312021 (2024).
  • DOI: 10.1083/jcb.202312021
  • Stress Granule Dysfunction via Chromophore-Associated Light Inactivation.
  • Koizumi T, Fujimoto A, Kawaguchi H, Kurosaki T, Kitamura A
  • ACS Omega, 9(19), 21298-21306 (2024).
  • DOI: 10.1021/acsomega.4c01469
  • Protocol for in vitro phospholipid synthesis combining fatty acid synthesis and cell-free gene expression.
  • Matsumura R, Sato G & Kuruma Y.
  • STAR Protoc., 5(2), 103051 (2024).
  • DOI: 10.1016/j.xpro.2024.103051
  • Periodic Alignment of Binary Droplets via a Microphase Separation of a Tripolymer Solution under Tubular Confinement.
  • Syono M, Aburatani K, Yanagisawa M, Yoshikawa K, Shioi A
  • ACS Macro Lett., 13(2), 207-211 (2024).
  • DOI: 10.1021/acsmacrolett.3c00689
  • Liquid DNA Coacervates form Porous Capsular Hydrogels via Viscoelastic Phase Separation on Microdroplet Interface.
  • Morita M, Sakamoto T, Nomura SM, Murata S, Yanagisawa M, Takinoue M
  • Adv. Mater. Interfaces, 11(13), 2300898 (2024).
  • DOI: 10.1002/admi.202300898
  • Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation.
  • Shinoda S, Sakai Y, Matsui T, Uematsu M, Koyama-Honda I, Sakamaki J, Yamamoto H, Mizushima N
  • eLife, 12, RP92189 (2024).
  • DOI: 10.7554/eLife.92189.3
  • Multimolecular Competition Effect as a Modulator of Protein Localization and Biochemical Networks in Cell-Size Space.
  • Nishikawa S, Sato G, Takada S, Kohyama S, Honda G, Yanagisawa M, Hori Y, Doi N, Yoshinaga N, Fujiwara K
  • Adv. Sci., 11(6), 2308030 (2023).
  • DOI: 10.1002/advs.202308030
著書
  • IUPAB京都2024年会議における座談会：我々の生物物理学の次の50年を夢見て（後半）
  • 林 久美子, Gerhard Hummer, Jerelle A. Joseph, Rong Li, 永井 健治, 大浪 修一, Feng Zhang, 北村 朗, 冨樫 祐一, 角五 彰, 藤原 郁子, 小松崎 民樹（2025）．
  • 生物物理, 65(2), 101–113.
  • DOI: 10.2142/biophys.65.101
  • IUPAB京都2024年会議における座談会：我々の生物物理学の次の50年を夢見て（前半）
  • 林 久美子, Gerhard HUMMER, Jerelle A. JOSEPH, Rong LI, 永井 健治, 大浪 修一, Feng ZHANG, 北村 朗, 冨樫 祐一, 角五 彰, 藤原 郁子, 小松崎 民樹
  • 生物物理, 65(1), 35–46.
  • DOI: 10.2142/biophys.65.35